USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: FAAA_HUMAN USC-OGP 2-DE database:  FAAA_HUMAN FAAA_HUMAN General information about the entry View entry in simple text format Entry name FAAA_HUMAN Primary accession number P16930 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Fumarylacetoacetase; Short=FAA; EC=3.7.1.2 {ECO:0000250|UniProtKB:P35505}; AltName: Full=Beta-diketonase; AltName: Full=Fumarylacetoacetate hydrolase;. Gene name Name=FAH Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0945: pI=6.38; Mw=42003 SPOT OGP-0946: pI=6.62; Mw=41904 Cross-references UniProtKB/Swiss-Prot P16930; FAAA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name FAAA_HUMAN Primary accession number P16930 Secondary accession number(s) B2R9X1 D3DW95 Q53XA7 Sequence was last modified on  August 1, 1992 (version 2) Annotations were last modified on  March 15, 2017 (version 173) Name and origin of the protein Description RecName: Full=Fumarylacetoacetase; Short=FAA; EC=3.7.1.2 {ECO:0000250|UniProtKB:P35505}; AltName: Full=Beta-diketonase; AltName: Full=Fumarylacetoacetate hydrolase; Gene name Name=FAH Encoded on Name=FAH Keywords Acetylation; Alternative splicing; Calcium; Complete proteome; Direct protein sequencing; Disease mutation; Hydrolase; Magnesium; Metal-binding; Phenylalanine catabolism; Phosphoprotein; Reference proteome; Tyrosine catabolism. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M55150; AAA52422.1; -; mRNA EMBL BT007160; AAP35824.1; -; mRNA EMBL AK313951; BAG36668.1; -; mRNA EMBL BX537608; CAD97795.1; -; mRNA EMBL AC087761; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471136; EAW99120.1; -; Genomic_DNA EMBL CH471136; EAW99121.1; -; Genomic_DNA EMBL BC002527; AAH02527.1; -; mRNA EMBL X51728; CAA36016.1; -; mRNA CCDS CCDS10314.1; -. [P16930-1]; . PIR A37926; A37926; . RefSeq NP_000128.1; NM_000137.2. [P16930-1]; . UniGene Hs.73875; -; . ProteinModelPortal P16930; -; . SMR P16930; -; . BioGrid 108479; 11; . IntAct P16930; 6; . STRING 9606.ENSP00000261755; -; . DrugBank DB01832; 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid; . DrugBank DB01762; Acetoacetic Acid; . DrugBank DB01677; Fumarate; . iPTMnet P16930; -; . PhosphoSitePlus P16930; -; . SwissPalm P16930; -; . BioMuta FAH; -; . DMDM 119778; -; . OGP P16930; -; . REPRODUCTION-2DPAGE IPI00031708; -; . EPD P16930; -; . MaxQB P16930; -; . PaxDb P16930; -; . PeptideAtlas P16930; -; . PRIDE P16930; -; . Ensembl ENST00000261755; ENSP00000261755; ENSG00000103876. [P16930-1]; . Ensembl ENST00000407106; ENSP00000385080; ENSG00000103876. [P16930-1]; . Ensembl ENST00000539156; ENSP00000454271; ENSG00000103876. [P16930-2]; . Ensembl ENST00000561421; ENSP00000453347; ENSG00000103876. [P16930-1]; . GeneID 2184; -; . KEGG hsa:2184; -; . UCSC uc002bfm.3; human. [P16930-1]; . CTD 2184; -; . DisGeNET 2184; -; . GeneCards FAH; -; . HGNC HGNC:3579; FAH; . HPA HPA041370; -; . HPA HPA044093; -; . MalaCards FAH; -; . MIM 276700; phenotype; . MIM 613871; gene; . neXtProt NX_P16930; -; . OpenTargets ENSG00000103876; -; . Orphanet 882; Tyrosinemia type 1; . PharmGKB PA27977; -; . eggNOG KOG2843; Eukaryota; . eggNOG COG0179; LUCA; . GeneTree ENSGT00390000008646; -; . HOGENOM HOG000256845; -; . HOVERGEN HBG001919; -; . InParanoid P16930; -; . KO K01555; -; . OMA SKSNFKH; -; . OrthoDB EOG091G00CM; -; . PhylomeDB P16930; -; . TreeFam TF315211; -; . BioCyc MetaCyc:HS02536-MONOMER; -; . Reactome R-HSA-71182; Phenylalanine and tyrosine catabolism; . UniPathway UPA00139; UER00341; . ChiTaRS FAH; human; . GeneWiki Fumarylacetoacetate_hydrolase; -; . GenomeRNAi 2184; -; . PRO PR:P16930; -; . Proteomes UP000005640; Chromosome 15; . Bgee ENSG00000103876; -; . CleanEx HS_FAH; -; . ExpressionAtlas P16930; baseline and differential; . Genevisible P16930; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0004334; F:fumarylacetoacetase activity; EXP:Reactome; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0006527; P:arginine catabolic process; IEA:Ensembl; . GO GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome; . GO GO:0006572; P:tyrosine catabolic process; TAS:ProtInc; . Gene3D 2.30.30.230; -; 1; . Gene3D 3.90.850.10; -; 1; . InterPro IPR005959; Fumarylacetoacetase; . InterPro IPR011234; Fumarylacetoacetase_C-rel; . InterPro IPR015377; Fumarylacetoacetase_N; . PANTHER PTHR43069; PTHR43069; 1; . Pfam PF01557; FAA_hydrolase; 1; . Pfam PF09298; FAA_hydrolase_N; 1; . SUPFAM SSF56529; SSF56529; 1; . SUPFAM SSF63433; SSF63433; 1; . TIGRFAMs TIGR01266; fum_ac_acetase; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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